The computer seems to be terriibly affected and disabled, that even any program from a pen drive would fail to run as expected.
So, the easiest option is to run an online scan (if possible). And the best online scan for viruses, and spyware is available at Trend house. http://housecall.trendmicro.com/ is the url. all you have to do is launch the Housecall from within that site.
If that option is not suitable for you, then i would suggest you to download the following programs into the pen drive and run each one of them in the affected computer.
a) Spybot search and destroy - http://www.safer-networking.org/en/mirrors/index.html is the link to the latest version. Please install after you download and run it. You should figure out all the spy stuff and be able to clean. you might require a reboot for some ones.
b) Malware bytes - You can download the gree version from http://download.cnet.com/Malwarebytes-Anti-Malware/3000-8022_4-10804572.html?part=dl-10804572&subj=dl&tag=button. It is powerful and can remove all malicious piece of softwares on your machine. Install and run on all the drives of the affected computer. Note: This is slower than spybot, but ensures that many malwares that goes undetected by Spybot are caught and cleaned.
Install an Antivirus after you clean up the system. I would suggest TrendMicro's antivirus products.