You Can Check That If In Textbox Some Value Or Not.
Using RequiredFieldValidator You Can Achieve This On The Textbox.
Take RequiredFieldValidator From The Validation Control & Set It's Property.
ControlToValidate : In This Property You Have To Set Your Textbox For Which You Want Validation. When Your Click On This It Will Display All Control Of Your From From That Select Your Textbox. Suppose Here "txtValue".
Error Message : Using This Property You Can Set Appropriate Message To The User.
Now If In The Textbox No Value Then It Will Give Error Message To The User.
Using This You Can Solve Your Problem...